TECHNOLOGY OF PROCESSING VEGETABLE RAW MATERIAL IN A THERAPEUTIC BIOLOGICAL ACTIVE NATURAL COMPLEX OF MEDICINAL AND PREVENTIVE DETERMENATION

Authors

  • Olga G. Pozdnyakova Author
  • Galina A. Belavina Author
  • Aleksandr A. Avstrievskih Author
  • Valeriy M. Poznyakovsky Author

Abstract

The article deals with the technology of production of the encapsulated form of a new specialized
product containing a biologically active natural complex of extracts of medicinal plants:
Echinacea Purpurea and licorice root. Pharmacological characteristics of the active principles of
prescription components proved the functional orientation of the specialized product and its synergistic
properties in relation to metabolic support of the immune system. The quantitative composition
was chosen according to the regulation of the composition of standard prescriptions approved
by the State pharmacological Committee. An innovative technology of the encapsulated
form of biologically active additives in the form of biologically active natural complex containing:
mg/1 capsule weighing 0.6 g: Echinacea purple extract – 60, at least – 1.5; ascorbic acid –
60; rutin – 30; licorice root extract – 20; zinc citrate - 13.4; sodium Selenite 0.014. The adjustable
technological parameters of production, ensuring the preservation of biologically active components
of the formulation and their functional properties were determined experimentally. The developed
technology includes the following main stages of production: preparation of raw materials,
preparation of semi-product 1 and semi-product 2, preparation of a mixture for encapsulation,
encapsulation and dust control, obtaining liquid extraction, thickening of the liquid extract, obtaining
a dry extract by spray drying. Gelatin capsules combine the prescription ingredients, protect
the contents from the effects of adverse environmental factors, provide the necessary speed of
delivery of biologically active components to the target cell and localization of action. Regulated
indicators of nutritional value are established. The effectiveness and functional orientation of the
developed product have been proven in clinical studies in comparison with drug therapy of the
upper airways with the provision of anti-inflammatory, adaptogenic and immunomodulatory effects.

Author Biographies

  • Olga G. Pozdnyakova

    Cand.Sci. (Eng.), Associate Professor, Associate Professor of the Department of Agrobiotechnology

  • Galina A. Belavina

    Postgraduate Student of the Department of Agrobiotechnology

  • Aleksandr A. Avstrievskih
    Dr. Sci. (Eng.), Professor, General Director
  • Valeriy M. Poznyakovsky

    Dr.Sci. (Eng.), Professor, head of scientific and educational center «Processing of agricultural raw materials and food technologies», Head of Department «Food industry and functional nutrition», Honored Scientist of the Russian Federation

Published

2019-09-30

Issue

Section

Pharmaceutical and Food Engineering