SYNTHESIS AND HALOCYCLIZATION OF ALLYL DERIVATIVES OF 4,5-DIHYDRO-1,3-THIAZOL-2-THIONE

Abstract

2-Propenyl-(2-methyl-1-propenyl-, 2-butenylthio- and (3-methylbutenyl-)thio4,5-dihydro-1,3-thiazoles are synthesized by alkylation of 4,5-dihydro-1,3-thiazol2-thione. These products were researched in halocyclization reactions with iodine and bromine. 3-(halomethyl)-2,3,5,6-tetrahydrothiazolo[2,3-b]thiazolium and 6-halo-3,5,6,7-tetrahydro-2Hthiazolo[2,3-b]thiazinium halides were formed. The structure of all the synthesized compounds was confirmed by 1_H NMR and gas chromatography-mass spectrometry.